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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
Drug Name
Drug ID
ATC Code
DrugBank ID
KEGG ID
PubChem ID
CAS RN
Molecular Formula
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ADR Ontology
ADR Term
Respiratory depression
ADR ID
BADD_A03808
ADR Hierarchy
17
Nervous system disorders
17.02
Neurological disorders NEC
17.02.05
Neurological signs and symptoms NEC
17.02.05.047
Respiratory depression
22
Respiratory, thoracic and mediastinal disorders
22.02
Respiratory disorders NEC
22.02.01
Breathing abnormalities
22.02.01.010
Respiratory depression
Description
Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) [MeSH]
MedDRA Code
10038678
MeSH ID
D012131
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Depression respiratory | Respiration depressed | Respiratory depression | Respiratory depression postoper | Central respiratory depression | Respiratory Insufficiency | Respiratory Failure | Respiratory Depression | Ventilatory Depression | Depressions, Ventilatory
ADR Related Proteins
Protein Name
UniProt AC
TTD Target ID
Not Available
Not Available
Not Available
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00963
Fosaprepitant dimeglumine
-
-
BADD_D00970
Fosphenytoin
0.002028%
BADD_D00972
Fospropofol disodium
-
-
BADD_D00979
Furosemide
0.000095%
BADD_D00981
Gabapentin
0.000464%
BADD_D00982
Gabapentin enacarbil
0.006362%
BADD_D00987
Gadofosveset
-
-
BADD_D01016
Gentamicin
-
-
BADD_D01054
Haloperidol
0.001654%
BADD_D01075
Homatropine
-
-
BADD_D01084
Hydrocodone
-
-
BADD_D01096
Hydromorphone
0.002477%
BADD_D01102
Hydroxybutanoic acid
-
-
BADD_D01111
Hydroxyzine
0.000045%
BADD_D01112
Hydroxyzine hydrochloride
-
-
BADD_D01114
Hyoscyamine
-
-
BADD_D01120
Ibuprofen
-
-
BADD_D01134
Iloperidone
0.000602%
BADD_D01178
Iodixanol
-
-
BADD_D01198
Iron dextran
-
BADD_D01203
Isoflurane
-
-
BADD_D01225
Kadain
-
-
BADD_D01228
Ketamine
0.003941%
BADD_D01229
Ketamine hydrochloride
-
-
BADD_D01232
Ketorolac
-
-
BADD_D01233
Ketorolac tromethamine
-
-
BADD_D01243
Lamotrigine
0.001289%
BADD_D01253
Lenalidomide
-
-
BADD_D01265
Levetiracetam
-
-
BADD_D01275
Levofloxacin
-
-
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